Science first
We aren’t just another health brand—Tally Health was born in the lab, driven by our scientists’ shared vision to put the power of cutting-edge aging science in your hands. From our longevity formulations and groundbreaking TallyAge™ Test to pioneering research led by our in-house scientists, every innovation we bring to you is designed to transform the way you live today, so you can thrive tomorrow. That’s how Tally puts science — and you — first.
Science with standards
Our pursuit for living healthier, longer is only matched by our relentless pursuit for quality. All ingredients in Tally Health supplements must adhere to three uncompromising criteria:
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Safe and well-tolerated
There must be multiple double-blind, randomized, placebo-controlled human clinical trials indicating that a specific dose is safe and well-tolerated. -
Targets hallmarks of aging
There should be strong mechanistic evidence indicating that each molecule can alleviate established hallmarks that underlie and drive aging. -
Published longevity benefits
There should be peer-reviewed published data in small mammals that ingredients extend lifespan and/or enhance aspects of healthspan.
Relentless innovation
Tally Health scientists don't just follow the science, they advance it. Explore leading longevity research published by Tally's in-house science team.
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Human age reversal: Fact or fiction?
An overview of interventions and factors linked to a younger molecular age, as predicted by aging clocks.
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A set of common buccal CpGs that predict epigenetic age and associate with lifespan-regulating genes
We review the literature on predicting epigenetic age from buccal (cheek) tissue, build a proof of concept buccal clock, and highlight interesting genes that tie the clock to aging biology.
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Glycine and aging: Evidence and mechanisms
An in depth overview of the literature surrounding glycine metabolism and its links to aging. Glycine is an important ingredient in our Amplify formulation.
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Apigenin: a natural molecule at the intersection of sleep and aging
An exploration of the scientific evidence for a key ingredient in our Restore supplement.
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CheekAge: a next-generation buccal epigenetic aging clock associated with lifestyle and health
A deep dive into CheekAge, an epigenetic buccal (cheek) clock that is the inspiration for our TallyAge™ test. In this work we demonstrate that CheekAge is accurate and associates with lifestyle and health factors. We additionally dissect genes and biological processes connected to CheekAge and compare this model to other epigenetic clocks.
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CheekAge, a next-generation epigenetic buccal clock, is predictive of mortality in human blood
We demonstrate that CheekAge, the epigenetic clock we developed that is the inspiration for the TallyAge™, significantly associates with mortality in a population of older adults.
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Contextualizing aging clocks and properly describing biological age
What is biological age? In this treatise we argue for the importance of detangling this abstract concept from epigenetic clocks and other biomarkers of aging.
Our cutting-edge epigenetic test
Imagine discovering how you’re aging at a cellular level with a painless cheek swab. It’s possible with the TallyAge™ Test, which measures unique DNA methylation patterns that are influenced by health and lifestyle and change over time. Our next-generation test was trained on the largest DNA methylation adult cheek swab dataset: over 8,000 diverse individuals spanning a chronological age range of 18-100 years.
Here’s what makes the TallyAge™ Test unique:
- Generalizable: Trained on a large diverse cohort of healthy adults
- Comprehensive: Uses over 200,000 sites across the entire genome
- Powerful: associates with lifestyle factors and health factors including mortality risk
- Convenient: a simple cheek swab you do at home
- Optimized for accuracy and reproducibility
Supplements that target aging at the source
Our longevity supplements are thoughtfully crafted blends of scientifically validated ingredients, delivering results that single-ingredient supplements can’t match. Each formulation supports vital functions like energy, focus, sleep, immunity, and cellular health—individually powerful and even more impactful when used together. This approach targets the complexities of aging to optimize health at a cellular level.
Your longevity.
Your way.
Experience Tally Heath's holistic suite of science-backed offerings. Benchmark, track and change the way you age today.
