Immunity Support
Defend
$69.00
Defend is designed to promote a healthy, vibrant immune system while simultaneously targeting immune-related aging hallmarks.
Risk-free subscription • Cancel anytime
Defend
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Vegan
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Non-GMO
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Gluten free
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9 major allergen free
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Endotoxin-free
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No Preservatives
Boost immunity at a cellular level
Defend is designed to:
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Help address inflammaging
Quercetin helps remove "zombie cells" (senescent cells) and moderate the expression of pro-inflammaging molecules 1,2,3
- Javadi et al. Journal of the American College of Nutrition 2017.
- McCluskey et al. Respiratory Research 2024.
- Li et al. Nutrients 2016.
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Support healthy immune function
Vitamin D3 helps the immune system mount a response 9,10
- Joliffe et al. The Lancet Diabetes & Endocrinology 2021.
- Aranow. Journal of Investigative Medicine 2011.
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Encourages healthy white blood cell activity
The antioxidant vitamin C helps kick white blood cells into gear 8
- Van Gorkom et al. Antioxidants (Basel) 2018.

Trusted ingredients
Our pursuit for living healthier, longer is only matched by our relentless pursuit for quality. If an ingredient doesn’t meet our standards, we don’t use it.
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Formulated by scientists
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Ingredients backed by peer-reviewed research
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Premium-quality, lab-tested ingredients
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Third-party safety certified

Research-backed ingredients
Our formulas are made with a powerful combination of ingredients that have been shown in research studies to promote longevity and improve healthspan.
Scientific References
- Javadi et al. The Effect of Quercetin on Inflammatory Factors and Clinical Symptoms in Women with Rheumatoid Arthritis: A Double-Blind, Randomized Controlled Trial. Journal of the American College of Nutrition 2017
- McCluskey et al. Quercetin improves epithelial regeneration from airway basal cells of COPD patients. Respiratory Research 2024
- Li et al. Quercetin, Inflammation and Immunity. Nutrients 2016
- Stier et al. Immune-modulatory effects of dietary Yeast Beta-1,3/1,6-D-glucan. Nutrition Journal 2014
- Mah et al. Soluble and Insoluble Yeast β-Glucan Differentially Affect Upper Respiratory Tract Infection in Marathon Runners: A Double-Blind, Randomized Placebo-Controlled Trial. Journal of Medicinal Food 2020
- Haase and Rink. The immune system and the impact of zinc during aging. Immunity & Ageing 2009
- Nault et al. Zinc for prevention and treatment of the common cold. Cochrane Database of Systematic Reviews 2024
- Van Gorkom et al. Influence of Vitamin C on Lymphocytes: An Overview. Antioxidants (Basel) 2018
- Jolliffe et al. Vitamin D supplementation to prevent acute respiratory infections: a systematic review and meta-analysis of aggregate data from randomised controlled trials. The Lancet Diabetes & Endocrinology 2021
- Aranow. Vitamin D and the immune system. Journal of Investigative Medicine 2011
- Javadi et al. The Effect of Quercetin on Inflammatory Factors and Clinical Symptoms in Women with Rheumatoid Arthritis: A Double-Blind, Randomized Controlled Trial. Journal of the American College of Nutrition 2017
- Van Gorkom et al. Influence of Vitamin C on Lymphocytes: An Overview. Antioxidants (Basel) 2018
- Beyer. The role of ascorbate in antioxidant protection of biomembranes: interaction with vitamin E and coenzyme Q. Journal of Bioenergetics and Biomembranes 1994
- Hahn et al. Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial. British Medical Journal 2022