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The future of healthy aging

Science-backed tools designed to improve your healthspan and longevity.

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  • Sharpen
  • Sharpen
  • Sharpen
  • Sharpen Supplement Facts
  • Sharpen

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  • 60 Capsules
  • 30-Day Supply
4.8 | 10,174+ ORDERS
Third-party safety certified

Sharpen Your Mind, Every Day

Five Ingredients. Backed By The Science of Why Brains Age.

  • BEST VALUE $74.00 $62.90
  • $74.00

Sharpen is designed to unlock better memory, clearer thinking, and improved focus as you age.

  • Clearer focus, less brain fog
  • Supports memory and recall
  • Built for the long game

Free shipping • Pause or cancel any time

HSA/FSA eligible via TruMed

Sharpen

Brain Health

$74.00

  • Vegan
  • Non-GMO
  • Gluten free
  • 9 major allergen free
  • Endotoxin-free
  • No preservatives

Brain Health + Longevity Formulation

In One Dose of Sharpen

Clean ingredients, no filler. Each one dosed at levels studied in human research and chosen to address hallmarks of aging.

  • Taurine

    Taurine

    Taurine supports mitochondrial function and helps buffer the oxidative stress that builds up with age

    1,000mg

  • Choline

    Choline

    Choline fuels acetylcholine production, the neurotransmitter your brain relies on for focus and memory

    200mg

  • Vitamin B12

    Vitamin B12

    Vitamin B12 supports nerve function and energy metabolism, helping clear the fog that slows you down

    2.4mcg

  • L-methylfolate

    L-methylfolate

    L-methylfolate is the active form of folate your brain uses to build mood-regulating neurotransmitters

    400 mg DFE

  • Vitamin B6

    Vitamin B6

    Vitamin B6 helps convert amino acids into serotonin and dopamine, key drivers of focus and mood

    1.7 mg

Manufactured in the USA with global ingredients

Why Tally Health

Built to address the biology of aging.

Every ingredient has to clear three bars before it made it into our signature formula. If an ingredient doesn't meet all three, it doesn't go in the capsule.

  • Proven Safe

    Proven safe and well-tolerated in double-blind placebo-controlled human trials

  • Targets Root Causes

    Strong mechanistic evidence it addresses a hallmark of aging

  • Backed by Real Data

    Published lifespan and healthspan data in animal models

  • Altered intercellular communication
  • Cellular senescence
  • Chronic inflammation
  • Deregulated nutrient-sensing
  • Disabled macroautophagy
  • Dysbiosis
  • Epigenetic alterations
  • Genomic instability
  • Loss of proteostasis
  • Mitochondrial dysfunction
  • Stem cell exhaustion
  • Telomere attrition

Changes You Can Feel

Discover how Sharpen helps enhance your health overnight and over time.

  • 1 week

    May observe early, subtle enhancements in cognition

  • 4 weeks

    Homocysteine levels are expected to drop in response to consistent supplementation with the B-vitamin complex

  • 3 months

    May observe more noticeable increases in various cognitive areas, including focus, memory, and attention

  • 6 months

    Pathways that bolster brain aging and wellness, including cholinergic signaling, are expected to be strongly supported

Within 12 months, over 62% of Tally Health members lowered their epigenetic age by an average of 2+ years

Verified 5 Star Reviews

Our community loves Sharpen

  • "I've been looking for something to help fight the brain fog I experience throughout the day. I noticed a difference in my memory and recall since taking Tally Health's Sharpen supplement daily."
    Amy Tally Subscriber
  • "I love this product! Felt the difference immediately."
    Ana Tally Subscriber
  • "After trying it for a few weeks, I noticed a subtle but steady improvement in mental clarity and energy levels."
    Garret M. Tally Subscriber

Powerful solo. Unbeatable combined.

Our scientist-formulated supplements are expertly stacked with synergistic ingredients to help accelerate your health goals.